German club Bayer Leverkusen has announced that Jamaican winger Leon Bailey will be out of action for several weeks because of a muscle tear. The 21-year-old picked up the injury during the first half of the club’s opening group match in the UEFA Champions League against Lokomotiv Moscow on Wednesday. He was substituted at half-time. The injury could also force Bailey to miss the Reggae Boyz’s Concacaf Nations League match against Aruba on October 12. The match will be played at the National Stadium in St Andrew. Bailey has scored two goals in six games for Bayer this season. We want to hear from you! Send us a message on WhatsApp at 1-876-499-0169, email us at email@example.com or firstname.lastname@example.org.
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11 11 11 11 11 22. Nacer Chadli (left wing) 5. Jan Vertonghen (centre back) – see the full line up, in squad number order, by clicking the arrow above 11 11 11 25. Joshua Onomah (attack midfield) 11 11 27. Kevin Wimmer (centre back) 33. Ben Davies (left back) 7. Heung-Min Son (striker) Tottenham Hotspur and Leicester City must be sick of the sight of each other.The two Premier League sides face each other for the third time in ten days on Wednesday night as they slug it out for a place in the FA Cup fourth round.The first clash between the two sides at White Hart Lane ended in a 2-2 draw as Harry Kane slotted home a late penalty, forcing the tie to a replay at the King Power Stadium tonight.Claudio Ranieri’s men will be full of confidence given the Foxes’ 1-0 Premier League win seven days ago, when Robert Huth’s header from a corner beat Hugo Lloris.But with both teams likely to field much-changed it could end up being a lottery in Leicester as a tie with Colchester United awaits.Mauricio Pochettino was thankful to get through a 4-1 victory over Sunderland with no new injuries but he does appear worried about his squad being burned out.Clinton N’Jie remains out, while Ryan Mason and Alex Pritchard are also absentees.Click the right arrow above to see our predicted Tottenham XI… 13. Michel Vorm (goalkeeper) 11 28. Thomas Carroll (central midfield) 11. Erik Lamela (right wing) 16. Kieran Trippier (right back) 6. Nabil Bentaleb (central midfield)
Two strikes from Lucas Joao saw Sheffield Wednesday beat promotion-chasing Derby 2-0 at Hillsborough.The victory was manager Jos Luhukay’s first league win since taking charge, putting a temporary halt on their drop towards the relegation zone.The result saw Derby fail to put the pressure on second-placed Aston Villa and leave them with only one win from their last five games.Joao tucked away the first goal clinically, then scored with a stunning solo effort two minutes into the second half. The travelling team applied the pressure early on, but the Owls defended resiliently to cling onto just their fourth home clean sheet of the season.Wednesday, who were seeking back-to-back home wins over Derby for the first time since 1987, made seven changes from Saturday’s 1-1 draw at Barnsley, as Luhukay continued the search for his first three points.The changes seemed to have an impact, as the Owls started brightly and 21-year-old Sean Clare, who impressed on his first league start, flashed a shot wide before Frederico Venancio nodded a corner straight at ‘keeper Scott Carson.The home side then took the lead after a swift move, when Adam Reach lofted a pass into the box towards Jack Hunt. Hunt calmly laid the ball off to Joao (18) who slotted the ball into the bottom right corner with his first touch.Andreas Weimann wasted Derby’s best chance of the half, when he headed Chris Baird’s cross narrowly wide of the front post.Hillsborough erupted just after the break, when Joao (47) doubled his side’s advantage from 25 yards. The Portuguese striker drove inside unchallenged and unleashed a powerful driven shot into the bottom corner from distance.The visitors, having not lost a league game since November, responded strongly. Bradley Johnson first had a penalty appeal waved away, after going down under pressure from Clare, then David Nugent headed high and wide before Tom Huddlestone saw his ambitious first-time shot blocked in the area.Weimann had another golden chance to put Derby on the scoresheet, as Matej Vydra rolled in behind, but Wednesday stopper Joe Wildsmith stood strong and thumped the stinging effort out for a corner.Sky Bet Championship’s top goal-scorer, Vydra, was next to be thwarted by Wildsmith. Almost inside the six-yard box, the striker looked set to score but Wildsmith managed to keep him at bay with his legs.The Rams continued to waste chances as Nugent selflessly released Johnson into the box and he scuffed his shot well wide. Weimann nearly got one back at the end. 1 Luhukay took over as Wednesday manager in January
Ferguson bounced back from losing to Liverpool with Aberdeen and eventually usurped them at the top with his Man United team He made notes and those tough lessons later saw the Dons beat Bayern Munich and then Real Madrid to win the Cup Winners Cup in 1983.Three years later he had the Man United job and set about usurping Liverpool as Britain’s most dominant side to become the team of the 90s and noughties.In fact, the last time Liverpool played Man United at Old Trafford as Premier League leaders was under Fergie’s watch in 1996. Laughter was banned and so nobody dared speak on the bus back from Liverpool to Aberdeen in 1980 for fear of Sir Alex Ferguson.The manager was not happy and was threatening to hit his Dons’ players in their pockets if they dared tried lightening the mood.A second round European Cup clash had ended in a 5-0 aggregate win for Liverpool, with a 4-0 loss coming at Anfield in what was Fergie’s first visit to the stadium – it has been suggested this is where his eagerness to knock them off their perch came from.“He actually banned the players from laughing on the team coach on our journey back,” Gordon Strachan recalled years later.“’Anyone who laughs will be fined £10,’ he said. And he kept looking back, trying to catch one of us out.”It was no shame to be beaten by Liverpool, who in Kenny Dalglish, Alan Hansen and Graeme Souness, had a strong Scottish edge. They were the best in the country.And after winning at Pittodrie, Liverpool welcomed Aberdeen to Anfield where they had not lost for 76 matches and they extended that record with a 4-0 win.Fergie, serving a touchline ban, could only watch on and pray for a quick and painless end.Writing in his book, A Light in the North, he said: “Towards the end of the game I told Willie Garner – I was still banned from the bench and Willie was acting as a runner for me – that we might as well put on young Neale Cooper for the experience. ‘And’, I said, ‘while you’re down there, tell the referee to blow the bloody whistle!’“That summed up how I felt. I was never so glad to get a game out of the way in my whole life.”Still, the loss helped him propel Aberdeen to the heights fans haven’t seen since. Getty Images – Getty 1
Dons improve to 20-3, host Wild Rose in regional semifinal FridayBy Paul LeckerSports ReporterMARSHFIELD — Tyler Fuerlinger scored a game-high 22 points as the Marshfield Columbus Catholic boys basketball team blasted Athens 84-42 in a WIAA Division 5 regional quarterfinal Tuesday night at Columbus Catholic High School.The Dons (20-3) rolled out to a 59-19 lead by halftime on their way to the big win.Nick Malovrh added 15 points, and Hunter Schultz had 13 for Columbus Catholic as 12 different Dons scored in the win.Columbus Catholic, the No. 2 seed in the regional bracket, moves on to a regional semifinal at home against No. 7 Wild Rose (14-9) on Friday. The winner goes on to play a regional final on Saturday. If the Dons win, they would host either Almond-Bancroft (21-2) or Wausau Newman Catholic (15-8) on Saturday night.Columbus has now won 20 games for the seventh time in school history and third time during the 11 years under coach Joe Konieczny (2007-08 and 2013-14).(Hub City Times Sports Reporter Paul Lecker is also the publisher of MarshfieldAreaSports.com.)Dons 84, Bluejays 42Athens 19 23 – 42Columbus Catholic 59 25 – 84ATHENS (42): Paul Mroczenski 12, Jared Belisle 10, Lane Nicholds 5, Benjamin Weller 4, Justin Kelly 4, Cade Ellenbecker 3, Colten Weiler 2, Guyler Luther 2. Record: 1-20.COLUMBUS CATHOLIC (84): Tyler Fuerlinger 22, Nick Malovrh 15, Hunter Schultz 13, Evan Nikolai 8, Matthias Gouin 7, Ethan Meece 4, Noah Taylor 4, Matt Olsen 3, Billy Young 2, Jared Mandel 2, Noah Hansen 2, Brett Loveland 2. Record: 20-3.
Computer Scientists at Princeton University have shown some very easy and creative methods to hackcryptographic key material with physical access to an encryptedmachine. Watch the video embedded below to find out how existingtechnology is really vulnerable against Cold Boot Attacks on Encryption Keys. All you need is a Duster spray can, if that, to cool the DRAM and extract the keys. The paper publishedalong with the video clearly outlines techniques for finding keysresiding in memory.The really cool part is that this technique doesn’treally hack into the encryption directly. Rather, it depends onscanning the encryption keys by accessing the contents of the RAM andthen extracting the data either by directly tampering with the RAM orby simply booting the computer from a USB drive. You can also read theindustry response and more details on these findings in the news.com article.It is not all bad news … Intel is planning on releasing atechnology code named “Danbury” which drastically reduces exposure tothe Cold boot attacks. Please note that Danbury technology will be part of the Intel vPro processor technology to be released later this year. Danbury uses dedicated platform hardware toprovide full disk encryption and the actual data encryption keys arenot kept in the DRAM. Although, Intermediate, or ‘wrapping’, keys usedto unlock data encryption keys are stored in DRAM temporarily,when the user is physically present or while remote IT operation hascontrol of the platform. These keys are subsequently deleted once nolonger needed, thus reducing the exposure significantly.I am also very happy to announce that Danbury SDK that can leveragedby software vendors to enhance encryption software will be made on the manageability developer communitylater this year. If you are interested to find out more about thistechnology or are interested in developing encryption software usingthis technology then feel free to leave a comment on this post.
Preconception screening can help couples prepare for the possibility their child may be born with a medical condition. Pregnancy comes with many unknowns. Perhaps one of the most harrowing is whether a child will be born healthy. Now, preconception screening—looking at the genetic risk factors of both partners before they conceive—is starting to answer that question.Many companies offer an array of screens to prospective parents. But these typically focus on a few hundred conditions, and couples often have to select which they’d like to be tested for. The problem is that some recessive conditions don’t show up in family histories, and the partners themselves may never have symptoms—making it unlikely they’ll ask the right questions. Now, researchers at the National Human Genome Research Institute’s Clinical Sequencing Exploratory Research Consortium are trying to expand screening options using whole-genome sequencing, which allows researchers to look broadly for carrier risk rather than screening specific genes or targeted panels.Science spoke with Sue Richards, a clinical medical geneticist at Oregon Health & Science University in Portland and a leader of the project, about findings published today in The American Journal of Human Genetics. This interview has been edited for length and clarity.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Q: How is your screen different than other preconception screens?A: We screened for many genes that are not on any current carrier screening panel … using whole-genome sequencing. Laboratories like mine have been offering carrier screening for many, many years, [but] the paradigm is shifting now from doing screening for single genes and targeted well-known variants [for disorders such as cystic fibrosis] to really a very large number of genes. [With whole-genome sequencing], we had the opportunity to cast a very, very large net.Q: What did you want to find out from this study?A: We wanted to know how patients choose what they want to learn about. And then, when they get their results, how do they use that information? The goal is to really empower people so they can make informed decisions about reproductive choices.Q: What did you do?A: Anyone who chose to be in the study would be screened for any life-threatening … genetic disorders. Then those results would be reported back. Then, we gave them a whole list of other types of genetic disorders that they could get carrier testing for—more than 700—and asked them if they wanted to know their results … for severe disorders, mild disorders, adult-onset disorders, and unpredictable disorders, where you wouldn’t be able to be sure about the phenotype. One of the findings … was that most people, over 90%, wanted all categories returned.Q: What else did you find?A: We found that the majority of people carry a variant, at least one. Some [carry] up to five disease-causing variants for a rare disorder. Between 3% to 4% of people had findings that were medically important for themselves. They had some gene [variant] that [meant] later in life they could develop cancer or cardiac disease or something like that.Q: What are the upsides? Why would people want to get this new kind of testing?A: Because we were using this technology of whole-genome sequencing, we were able to screen and offer people additional information about their own personal health. If you have a clinically actionable variant that for example is going to predispose you to have breast cancer or colon cancer, then we would report that finding if they wanted that. It was interesting that 99% wanted [medically actionable] information back. I think it speaks loudly to the fact that people want to know this information when they’re given that choice.Q: What are the downsides?A: A general practice in genetics for diagnostic testing is to also report those variants we can’t interpret, and we don’t know if they actually cause disease or don’t cause disease. … This is a huge problem. What we wouldn’t want to end up doing is having patients with great anxiety or having a prenatal diagnosis done for a variant of uncertain significance because you wouldn’t be able to interpret anything and that’s not making an informed choice. That’s not good knowledge—that could be harmful.Q: When will whole-genome prescreens be commercially available?A: It might be a little premature yet to do that. It’s close to being ready, but there were some regions of the genome that even this technology doesn’t get yet. There’s some common genetic disorders where the genes are very similar to other genes … this doesn’t work well for that. If there’s a repeat region, like in a fragile X, or Huntington disease, those kinds of regions are hard to screen for. In a very few years, we’re going to be ready, certainly technology wise.Q: Would you recommend this new kind of testing?A: Just because you can do more, should you do more? In this study, we were conservative in our approach, and we only reported variants we were quite confident were pathogenic, disease-causing variants. There’s going to be a discussion that continues in the genetics community. … When is the appropriate time to offer it? Let’s [not] do it until we’re really ready to do it right, because we don’t want to make mistakes.*Correction, 11 May, 9:47 a.m.: The image has been updated; the previous image showed an incorrect DNA helix. Getty Images/iStockphoto By Roni DenglerMay. 10, 2018 , 11:25 AM Should you get a genetic screen before having kids?
Kedar Jadhav’s first international century led India past Zimbabwe by 83 runs in the third one-day game and a series sweep on Tuesday.Jadhav’s 105 not out formed the backbone of the India innings at Harare Sports Club, rescuing the 2011 Cricket World Cup champion from 82 for 4 in a 144-run partnership with Manish Pandey.Pandey made 71, and India reached 276 for 5 in 50 overs.Zimbabwe was bowled out for 193, with allrounder Stuart Binny taking 3 for 55 for India with his seamers. Mohit Sharma, Harbhajan Singh and Axar Patel shared two wickets apiece.Murali Vijay was the surprising wicket taker when he trapped E Chigumbara leg before for 10.Touring with an under-strength team led by stand-in captain Ajinkya Rahane, India clinched a whitewash and got better during the series, winning games by four runs, 62 runs, and then by Tuesday’s comfortable margin.Earlier, Zimbabwe won the toss and elected to field. After 21.4 overs, the India were tottering at 82 for 4 before Jadhav and debutant Pandey stitched the vital partnership. Robin Uthappa was the other major contributor with 31 runs of 44 balls at number three. The men in blue finished 276 for 5 in their quota of 50 overs. Chasing, Zimbabwe built a base for themselves at 150 for 3 in the 35th over, led by Chamu Chibhabha’s 82. But the hosts lost their last seven wickets for 43 runs to hand India a 3-0 series sweep.Kedar Jadhav was adjudged the Man of the Match and Ambati Rayudu was awared the Man of the Series. The teams move on to a two-game Twenty20 series starting on Friday. advertisement