Stewardship / Resistance Scan for Mar 29, 2019

first_imgChinese surveillance study finds multidrug-resistant E coli in foodA surveillance study by Chinese scientists has found multidrug-resistant Escherichia coli strains in food products carrying the MCR-1 and blaNDM-1 resistance genes, and mobile genetic elements similar to those found in human strains, according to a paper yesterday in Eurosurveillance.Among the 1,166 non-repeated cephalosporin-resistant E coli isolates recovered from 2,137 samples of pork, beef, chicken, and shrimp bought at markets in Shenzen, China, from 2015 through 2017, the scientists identified 390 and 42, respectively, that were resistant to colistin and meropenem, and 5 isolates that were resistant to both antibiotics.Among the 390 colistin-resistant E coli isolates, the rate of resistance to colistin rose from 26% in 2015 to 46% in 2017, while rates of meropenem resistance in the 42 meropenem-resistant isolates increased from 0.3% in 2015 to 17% in 2017.Further screening found that all of the colistin-resistant isolates carried the MCR-1 gene and 36 of the 42 meropenem-resistant isolates carried the blaNDM-1 gene, with six harboring the blaNDM-5 gene; the five isolates that were resistant to both colistin and meropenem were carrying both MCR-1 and blaNDM genes. Notably, the scientists identified plasmids—in particular the ca 46kb IncX3 plasmid—that have been commonly reported in colistin- and carbapenem-resistant clinical isolates but not in isolates from animals and food. Conjugation experiments revealed that the colistin and meropenem resistance phenotypes of the 5 MCR-1 and blaNDM-bearing strains were transferable to other E coli strains of food origin.The authors of the study say the isolation of E coli strains harboring blaNDM-1 and MCR-1 that structurally resemble clinical strains has not previously been reported, and warn that the rising prevalence of these strains could mean an increase in severe, multidrug-resistant foodborne infections.”The increasing prevalence of Enterobacteriaceae strains carrying bla NDM and mcr-1 in food products will lead to increased colonisation of the human gastrointestinal tract with these Enterobacteriaceae strains, a phenomenon that has been associated with the high prevalence of drug-resistant infections in clinical settings,” they write. “Further surveillance of bla NDM-1 and mcr-1 in other food products is warranted.” Mar 28 Eurosurveill study Study in Georgia finds poor long-term outcomes for XDR-TB treatmentA study today in Open Forum Infectious Diseases reports high mortality among patients with extensively drug-resistant tuberculosis (XDR-TB) in the former Soviet republic of Georgia, with most deaths occurring post-treatment.In the retrospective population-based cohort study, researchers from Emory University and Georgia’s National Center for Tuberculosis and Lung Diseases assessed end-of-treatment and long-term outcomes in patients with XDR-TB. They also evaluated risk factors for poor outcomes. Patients were treated by directly observed therapy in accordance with 2011 World Health Organization (WHO) treatment guidelines for drug-resistant TB; the drug regimen did not include the newer agents bedaquiline and delamanid, which are now recommended under current WHO guidelines.From 2011 through 2013, 111 patients initiated treatment for XDR-TB; end-of-treatment outcomes were available for 106. Of those patients, 35 (33%) had a favorable outcome from initial XDR-TB treatment and 71 (67%) had an unfavorable outcome, with 16 (15.1%) dying. After cessation of initial XDR-TB treatment, an additional 20 of 90 (22.2%) patients who were alive at the end of treatment died, increasing the overall mortality rate to 34% (36 of 106). In multivariable analysis, the main factor for post-treatment mortality was unfavorable initial end-of-treatment outcome (adjusted odds ratio, 14.41; 95% confidence interval, 1.78 to 117.3).”The results of our study highlight the need for better surveillance during and after treatment for highly drug resistant TB,” the authors of the study write. “After treatment cessation, public health resources should focus on continual monitoring of patients given a significant risk of mortality and relapse.”Mar 29 Open Forum Infect Dis abstract Darden commits to buying chicken raised without antibiotics Multi-brand restaurant operator Darden Restaurants yesterday announced it will phase out the routine use of medically important antibiotics in its chicken supply chain by 2023.The commitment to buying chicken raised without medically important antibiotics is part of a wider animal welfare policy that the company, whose brands include Olive Garden and The Capital Grille, is adopting. The policy aims to increase mobility, lower injury and mortality rates, and reduce stress and fear among the farm animals in its supply chain.In addition to responsible use of antibiotics, Darden has identified humane housing, avoidance of pain, slaughter practices, and farm animal transportation as priority areas for improvement.Darden operates more than 1,700 restaurants in North America.Mar 28 Darden Restaurants press releaselast_img read more

Jason Momoa, Brad Pitt, George Clooney celebrated in new ‘People”s “Sexiest Man Alive” issue

first_imgABC/Rick Rowell(LOS ANGELES) — While it’s already known that EGOT winner John Legend has succeeded Idris Elba as People‘s Sexiest Man Alive, the magazine’s cover feature also celebrates less controversial picks in various categories.For example, Brad Pitt and Jason Momoa are part of the 28 “Men of the Year,” described as “standouts of modern-day sophistication.” They join the likes of current Men’s Health cover model and This Is Us star Sterling K. Brown, as well as Last Christmas heartthrob Henry Golding.And yes, Elba — who some might argue is eternity’s Sexiest Man — is included on the list as well.Speaking of eternally sexy, the magazine also highlights silver foxes like George Clooney, and the Social Security-eligible sexiness of 64-year-old Denzel Washington. They, Hugh Jackman, Matt Damon, and Bradley Cooper, are heralded in People‘s “Still Sexy After All These Years” category, which highlights former “Sexiest” cover stars.Here’s a roundup of People‘s choices:Men of the Year: Brad Pitt Jason MomoaSterling K. Brown Tom Hanks Paul Rudd Aaron Paul Henry GoldingMatt Czuchry Taika Waititi Desus & Mero Tony Dokoupil The Jonas Brothers Idris Elba Keanu Reeves Ben Platt Andrew ScottDavid Harbour Shawn Mendes Mena Massoud Bill HaderYahya Abdul-Mateen IITan France Mike ColterJohn KrasinskiMark Consuelos Still Sexy After All These Years (Former Sexiest Men Alive):  George Clooney (1997, 2006); David Beckham (2015); Denzel Washington (1996); Hugh Jackman (2008); Bradley Cooper (2011); Dwayne Johnson (2016); Matthew McConaughey (2005); Matt Damon (2007).Various:Sexiest Instagram:  Channing TatumSexiest Funny Guy: Trevor NoahSexiest Import:  Chris HemsworthSexiest New Dad:  Prince HarrySexiest Newly Single: Liam HemsworthSexiest Gym Addict:  Zac EfronSexiest Newcomer: Lil Nas XSexiest Reality Star: Antoni PorowskiSexiest TV Host: Terry CrewsSexiest Superhero: Tom HollandSexiest Heartthrob: David DobrikCopyright © 2019, ABC Audio. All rights reservedlast_img read more

Lewiinski’s bid for the Olympics

first_img1st Kristy Knight (18) 38pts2nd Peter Henshaw (16) 37pts3rd Kathy Doody (19) 37ptsNear Pins:  No 4 Ian Halfpenny, No 9 Reg McKay, No 12 Liam McGuinness, No16 Claude Harder.Pierre Bietry in action at this year’s Bangkok Marathon.Yes golf is soon to be an Olympic sport, but today’s headline for once isn’t about golf.  It’s about two much more physically demanding sports in running and swimming, as two of our regular players took time off the links to test themselves physically rather than mentally!Over the past weeks Pierre ‘The Magician’ Bietry has been in training for the Bangkok Marathon, whilst ‘The Principal” Jez Lees has been swimming hard in preparation for the Annual Pattaya Cross Bay Swim.Up in Bangkok, Pierre started at three o’clock in the morning outside the Royal Palace, and made it back in 4 hours 20 minutes.  Apparently Pierre started off at a leisurely 4.5km an hour but upped it to a very respectable 10 when he realized he had left partner Yui in charge of his wallet.Meanwhile here in Pattaya, Jez was competing in his second Cross Bay Swim.  A large contingent of golfing buddies turned out to wave him off from the Bali Hi Rescue Centre as he set out for the Dusit Resort 3.5km away.  Precisely 1 hour 6 minutes and 23 seconds later they welcomed him home in a very impressive 4th place.Jez Lees all set for the Pattaya Cross Bay Swim.Many thanks to all those who supported and donated to the worthy causes, and very well done to Pierre and Jez.  It seems someone who will for now remain nameless quipped that having now seen Jez play golf and swim, he should definitely stick to the latter.Talking of golf; no one knows when he will strike, but the jovial Colm Mullen never keeps ‘em waiting long.  The Irishman’s 39 points was the best on the day and it had to be that good to edge last week’s title boy Claude Harder who has taken a likening to the headlines, and fellow Irishman Terry, who were tied a shot adrift.  Terry’s card indicates he is about ready to blow his own whistle.  The Offaly gang leader Kevin was hovering close by.B Flight had the same number of Irishmen on the podium; Christy Good Knight taking the laurels with a splendid 38 points.  Peter ‘Don O Corleone’ Henshaw, Kathy Doody and Sim Davis were all locked on 37 points and they finished in that order on the resulting count-back.  Bad luck Sim!It was nice to see that quality golfer Andy Leach back in town again.Art O’Conner, Maurice Copan and Christy Knight split the ‘2’s pot.Monday, Nov. 22, Treasure Hills – StablefordA  Flight1st Terry Mangan (12) 35pts2nd Mike Nagle (13) 34pts3rd Ed Wyckoff (10) 34ptsB Flight1st Joe ‘Tynan (30) 38pts2nd Eddy Beilby (17) 35pts3rd Peter Henshaw (16) 33ptsWhat a difference a course makes!  And some distance (6,726 yds) and some dryness.  These same guys and girls and their same sacks of clubs took on the diabolical design of Yoshikazu Kato, who also laid out the Canyon course at one of Thailand’s most fabled courses, Blue Canyon.I should stop the article right there and leave the winners to their anonymity but we never do that.  Actually the player of the day and winner of B flight Joe ‘Sat nav’ Tynan was the only player to better his handicap – thus the odd murmurs of “sandbagger” at the presentation.  Seriously, Joe proved to be a most popular winner.  Eddy ‘The Eagle’ put in a fine 35 point haul for the silver and the ubiquitous Peter ‘Don Corleone’ was left to round out the flight.Ha!  I told you he was ready to pounce – Irelands’ Terry Mangan did all that was required to win the senior flight firing a steady 35 points.  Mike Nagle and Ed ‘The Right Honorable’ Wyckoff’ faced off in a count-back as both were a shot short; the count back victim was EdTen ‘2’s were recorded and each recipient won about as much as the cost of this week’s edition of the Mail.Wednesday, Nov. 24, St. Andrews – StablefordA Flight1st Seamus Cotter (11) 38pts2nd Steve Mascari (1) 37pts3rd John Bahng (11) 36ptsB Flight1st Pat Reagan (12) 41pts2nd Mike Nagle (13) 38pts3rd Tore Eliassen (14) 36ptsC Flight1st Eddy Beilby (17) 41pts2nd John Bresnchan (18) 39pts3rd Gerry Mernagh (17) 37ptsD Flight1st Jim Elphick (24) 38pts2nd Tim DeGrote (26) 37pts3rd Jim Bell (21) 3 ptsA large field enjoyed the special rates opportunity to play St Andrews and the always well conditioned course yielded a host of fine scores.Former owner of Lewiinski’s, and always a welcome addition, Steve Mascari made a rare appearance and showed he is still a leader of Pattaya’s best golfers with a super 37 points of his 1 handicap.  Seamus ‘the captain’ Cotter stopped it being a winning return though by bettering Steve by a single shot.  Last week’s headline boy John Bahng filled the flight with an even par round.The young man from Co. Dublin Pat Reagan took the laurels in B Flight and co-man of the match with a splendid 41 points.  Mike Nagle gained the silver with38 points leaving Tore Eliassen to fill the flight.Eddy the eagle took control of C Flight with a co-man of the match performance 41 points while John Bresnchan posted a very creditable 39 points for the silver.  Gerry Mernagh emerged from a three-way count-back over Peter Hedenburgh and Brian Carroll to round out the flightJim Elphick took the top spot in D Flight on 38 points and Tim DeGrote was a shot back for silver.  Jim ‘Houdini’ Bell and Bill Peach contested the bronze in a count-back, the scales tipping in Jims favour.David Hamilton, Colin Davis, Gavin Knox, Gerry Mernagh and Salim AlHarthy shared the ‘2’s pot.Friday, Nov. 26, Crystal Bay – StablefordA Flight1st Ed Wyckoff (10) 40pts2nd Andy Leach (5) 37pts3rd Jean-Pierre Gasser (7) 35ptsB Flight1st Lindsay Semple (12) 40pts2nd Gavin Knox (12) 37pts3rd Yui Bietry912) 36ptsC Flight1st Eddy Beilby (17) 37pts2nd Lou Szigligeti (20) 34pts3rd Jum Karagit (15) 34ptsFriday’s fixture saw the society venture to the well maintained Crystal Bay.The premier flight was led by Ed ‘The Right Honorable’ Wyckoff with an impressive 40 points and he was chased home by Andy leach who showed no symptoms of  jet lag for second.  Jean Pierre Grasser took third after a three-way tie that included Seamus ‘Captain’ Cotter and Peter Lenoury.Australian Lindsay Semple was co-man of the match and B Flight winner as he matched Ed’s card.  He was followed home by Scotland’s Gavin Knox and the girl on form Yui Bietry.The junior flight belonged to Eddy ‘the Eagle’ Beilby who made it a third visit this week to the pay window.  Aussie Lou ‘Zig Zag’ was second and the flight was completed by Jum Karagit who got the verdict in a count-back over the unlucky Paula Pederson.The story to this flight however belonged to Tim Degrout who arrived late at the course and started his round on the third hole after missing the first two.  He was only a shot away from making the podium at the end.Thierry Petremont, Takeshi Hakozaki San and Yui Bietry split the ‘2’s pot and Yui was two inches from an ace.Note: Lewiinski’s is situated on Pattaya Land Soi 1, Beach Road Soi 13/3 near to Walking Street.  Anyone wishing to play with us just pop in and add your name to the list or call Colin on 089 826 0764.  Transport is provided. PSC golf from Lewiinski’sSunday, Nov. 21, Green Valley – StablefordA Flight1st Colm Mullen (15) 39pts2nd Claude Harder (11) 38pts3rd Terry Mangan (12) 38ptsB Flightlast_img read more

Lenovo to launch Vibe K5 Note in India on August 1

first_imgLenovo has started sending out block your date media invites for an event scheduled for August 1 where the company will launch the Vibe K4 Note successor, the Vibe K5 Note. The company had recently started teasing the launch on Twitter, where it had said the Vibe K5 Note was to come to India in the coming weeks.Lenovo had launched the Vibe K5 Note first in China, and only recently in Thailand. The phone is a stark departure from the Vibe K4 Note from a design perspective, and features a premium all-metal body and rear-mounted fingerprint t scanner. The Vibe K4 Note was all-plastic in comparison.The Vibe K5 Note comes with a 5.5-inch fullHD LTPS display with a 1920 x 1080 pixels resolution and is powered by a 1.8GHz octa-core MediaTek Helio P10 processor coupled with Mali-T860 GPU and 2GB/3GB of RAM. The phone comes with 16GB of internal memory which is further expandable by up to 128GB via microSD card slot. The K4 Note was meanwhile powered by a 64-bit octa-core MediaTek processor with 3GB RAM and 16GB of internal memory. Also Read: Lenovo to launch Vibe K4 Note successor Vibe K5 Note in India in coming weeksThe dualSIM phone supports 4G LTE (VoLTE-ready) and runs Android 5.1 Lollipop-based Vibe UI.It sports a 13-megapixel camera on the rear with phase detection autofocus (PDAF) along with dualLED flash. There’s also an 8-megapixel camera on the front.The Vibe K5 Note uses a 3,500mAh battery which is non-removable. Dolby Atmos surround sound technology is supported out-of-the-box. The phone is available in the colours Gold and Silver in China and retails at 1,099 Yuan (roughly $167 or Rs 11,185).      advertisementlast_img read more